 | Shota Atsumi Assistant Professor Email: atsumi@chem.ucdavis.edu Phone:(530) 752-6595 Department of Chemistry, Graduate School of Science, Kyoto University, Ph.D. (2002) Postdoc Department of Biochemistry & Molecular Biophysics, University of Arizona (2002-2006) Dept. of Chemical and Biomolecular Engineering, University of California, Los Angeles (2006-2009) Appointed to faculty, July 2009 Group Page |
| Principal Research Interests |  |
An increased understanding of system properties underlying cellular networks enables us to construct novel systems by assembling the components and the control systems into new combinations. We are applying this approach to the field of metabolic engineering, which strives for the optimization of desired properties and functions, such as the production of valuable biochemicals. The production of valuable chemicals from microorganisms suites to solve some significant challenges, such as converting renewable feedstocks into energy-rich biofuels. Currently, our main focus is developing synthetic organisms capable of converting CO2 directly to biofuels. | |
| Representative Publications Directed evolution of thermophilic citramalate synthase for 1-propanol and 1-butanol biosynthesis from Escherichia coli, Atsumi, S. & Liao, J.C. Appl Environ Microbiol.74: 7802-7808 (2008) Metabolic Engineering for Advanced Biofuels Production from Escherichia coli Atsumi, S. & Liao, J.C. Curr Opin Biotechnol.19: 414-419 (2008) Non-Fermentative Pathways for Synthesis of Branched-Chain Higher Alcohols as Biofuels Atsumi, S., Hanai, T. & Liao, J.C. Nature 451: 86-89 (2008) Metabolic engineering of Escherichia coli for 1-butanol production, Atsumi, S., Can, A.F., Connor, M.R., Shen, C.R., Smith, K.M., Brynildsen, M.P., Chou, K.J., Hanai, T & Liao, J.C. Metab. Eng. Metab. Eng. 10: 305–311 (2008) A synthetic phage lambda regulatory circuit Atsumi, S. & Little, J.W. Proc. Natl. Acad. Sci. USA. 103: 19045-19050 (2006) Role of the lytic repressor in prophage induction of phage l as analyzed by a module-replacement approach Atsumi, S. & Little, J.W. Proc. Natl. Acad. Sci. USA. 103: 4558-4563 (2006) Regulatory circuit design and evolution using phage lambda Atsumi, S. & Little, J.W. Genes & Development 18: 2086-2094 (2004) Selections for constituting new RNA-protein interactions in catalytic RNP Atsumi, S., Ikawa, Y., Shiraishi, H. & Inoue, T. Nucleic Acids Res, 31: 661-669 (2003) Design and development of a catalytic ribonucleoprotein Atsumi, S., Ikawa, Y., Shiraishi, H. & Inoue, T. EMBO.J, 20: 5453-5460 (2001) | |