dd
Mark Mascal
Associate Professor

Email: mascal@chem.ucdavis.edu
Phone:(530) 754-5373

B.S., Western Illinois University, 1983.
M.S., University of Illinois at Urbana-Champaign, 1985.
Ph.D., University of London, 1988. Postdoctoral Fellow, University of Strasbourg, France, 1988-1990.
Lecturer, Loughborough University, UK, 1990-1991.
Lecturer, University of Nottingham, UK, 1992-1999.
Donald J. Cram Teacher-Scholar and Visiting Professor, UCLA 2000-2003.
Appointed to faculty, UC Davis, 2003.
Group Page
Principal Research Interests
The main theme of our research program is the application of synthetic organic chemistry to the study of molecular assemblies, molecular information, and bio-organic/biomaterials science. Current work is focused in four main areas: (i) the design and synthesis of novel self-organizing molecular systems, (ii) the design and synthesis of topologically interesting organic molecules, (iii) the design and synthesis of novel cyclophane-based host-guest systems, (iv) ab initio and hybrid QM/MM methods of modeling noncovalent interactions and protein-substrate binding.
Representative Publications

"From Molecular Ribbons to a Molecular Fabric" M. Mascal, J. Hansen, P. S. Fallon, A. J. Blake, B. R. Heywood, M. H. Moore, J. P. Turkenburg, Chem. Eur. J. 1999, 5, 381.

"S-Cylindrophanes: From Metal Tweezers to Metal Sandwiches" M. Mascal, J.-L. Kerdelhué, A. J. Blake, P. A. Cooke, Angew. Chem. Int. Ed. 1999, 38, 1968.

"The G-C DNA Base Hybrid: Synthesis, Self-Organization and Structural Analysis" M. Mascal, N. M. Hext, R. Warmuth, J. R. Arnall-Culliford, M. H. Moore, J. P. Turkenburg, J. Org. Chem. 1999, 64, 8479.

"The Vinylogous Witkop Cyclisation" E. L. Ruchkina, A. J. Blake, M. Mascal, Tetrahedron Lett. 1999, 40, 8443.

"Calixhydroquinones: a Novel Access to Conformationally Restricted, Meta-Substituted Calixarenes" M. Mascal, R. Warmuth, R. T. Naven, R. A. Edwards, M. B. Hursthouse, D. E. Hibbs, J. Chem. Soc. Perkin Trans. 1 1999, 3435.

"Protonic Conduction in Imidazole - a Solid-State 15N-NMR Study" B. S. Hickman, M. Mascal, J. J. Titman, I. G. Wood, J. Am. Chem. Soc., 1999, 121, 11486.

"On the Nature of Arene h6 Interactions in the Solid State and the Use of Cylindrophanes as Ligands for Sandwich Complexation of Metals with Longer-Range Interactions with the Benzene Ring" M. Mascal, J.-L. Kerdelhué, A. J. Blake, P. A. Cooke, R. J. Mortimer, S. J. Teat, Eur. J. Inorg. Chem., 2000, 485.

"Hydrogen Bonded Molecular Ribbons as Templates for the Synthesis of Modified Mineral Phases" S. Champ, J. A. Dickenson, P. S. Fallon, B. R. Heywood, M. Mascal, Angew. Chem. Int. Ed., 2000, 39, 2716.

"Breakdown of the Hydrogen Bond Strength-Length Analogy - a Revision" M. Mascal, C. E. Marjo, A. J. Blake, Chem. Commun., 2000, 1591.

"Azatriquinanes. Part 2. Synthesis of Azatriquinadiene and Azatriquinacene" M. Mascal, M. Lera, A. J. Blake, J. Org. Chem., 2000, 65, 7253.

"Structure and Polymorphism of the 10.10.10 Simmons and Park Cryptand" A. S. Batsanov, A. J. Blake, N. M. Hext, M. Mascal, Chem. Commun., 2001, 127.

"The Azatriquinenamine Trimer - a Novel Proton Chelate" M. Mascal, M. Lera, A. J. Blake, M. Czaja, A. Kozak, M. Makowski, L. Chmurzynski, Angew. Chem. Int. Ed., 2001, 3696.

"Azatriquinanes. Part 4. The Chemistry of Azatriquinenamine and its Bromination Products" M. Lera, A. J. Blake, C. Wilson, M. Mascal, J. Chem. Soc., Perkin Trans. 1, 2001, 3145.

"Anion-Aromatic Bonding: A Case for Anion Recognition by p-Acidic Rings" M. Mascal, A. Armstrong, M. D. Bartberger, J. Am. Chem. Soc. 2002, 124, 6274.

"The Energetics of Shooting Ions into the Dodecahedrane Cage" M. Mascal, J. Org. Chem. 2002, 67, 8644.

"Automatic Chiral Selection in a Thermodynamically Predisposed Metathesis Reaction" M. Mascal, I. G. Wood, T. Walsgrove, Org. Lett. 2003, 5, 2517.

"The Azaacepentalenide Anion: A New Aromatic, Bowl-Shaped Heterocycle" M. Mascal, J. Cerón Bertran, J. Am. Chem. Soc. 2005, 127, 1352.

"Interaction of Fullerenes with the Concave Surfaces of Perchloroazatriquinacene" D. Pham, J. Cerón Bertran, M. M. Olmstead, M. Mascal, A. L. Balch, Org. Lett. 2005, 7, in press.